7,3',4'-Trihydroxy-3-benzyl-2H-chromene


CAS No. : 1111897-60-9

1111897-60-9
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Cat. No. : HY-N2735
M.Wt: 270.28
Formula: C16H14O4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 1111897-60-9 :

7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC50 values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5µM [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus[1][2]. IC50 & Target:IC50: 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5 µM [H9N2][1]. In Vitro:7,3',4'-Trihydroxy-3-benzyl-2H-chromene (Compound 11) has potent NAs inhibitory activities with IC50 values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5 µM [H9N2], respectively[1].

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