INK4C-IN-3
CAS No. : 1111287-26-3
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| Cat. No. : | HY-123592 |
| M.Wt: | 336.34 |
| Formula: | C19H16N2O4 |
| Purity: | >98 % |
| Solubility: |
INK4C-IN-3 is a synthetic coumarin amide compound and a small-molecule inhibitor of INK4C (p18INK4C). INK4C-IN-3 promotes the ex vivo expansion of human and mouse hematopoietic stem cells. INK4C-IN-3 can be used in research related to hematopoietic stem cell expansion[1][2].
In Vitro:INK4C-IN-3 (compound 41) (administered continuously for 14 days) potently promotes the expansion of murine C57BL/6 CD34−LKS hematopoietic stem cells in vitro, with an ED50 of 9.92 nM[2].
INK4C-IN-3 (0.01-1 μM; 7 days) promotes the ex vivo expansion of human umbilical cord blood CD34+ hematopoietic stem cells[2].
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