8-Deazahomofolic acid
CAS No. : 111113-73-6
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| Cat. No. : | HY-124093 |
| M.Wt: | 454.44 |
| Formula: | C21H22N6O6 |
| Purity: | >98 % |
| Solubility: |
8-Deazahomofolic acid is an inhibitor of thymidylate synthase (TS) and other folate-related enzymes. 8-Deazahomofolic acid shows inhibitory activity against folate-dependent S. faecium, L. casei, and MTX (HY-14519) resistant strains. 8-Deazahomofolic acid also inhibits the growth of L1210 leukemia cells, with an IC50 value of 87.5 μM. 8-Deazahomofolic acid can be used in research on bacterial infections and tumors[1].
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