Nemazoline (hydrochloride)
CAS No. : 111073-18-8
(Synonyms: A-57219; SCH 40054)
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| Cat. No. : | HY-106798 |
| M.Wt: | 280.58 |
| Formula: | C10H12Cl3N3 |
| Purity: | >98 % |
| Solubility: |
Nemazoline hydrochloride (A-57219 hydrochloride) is selective α-adrenergic agent with α1-agonist/α2-antagonist activity, which is used as a nasal decongestant. Nemazoline hydrochloride produces decongestion by α1-mediated contraction of capacitance vessels, but not compromises blood flow by virtue of α2-antagonism. Nemazoline hydrochloride also blocks endogenous noradrenaline-mediated α 2-constriction of the resistance vessels[1].
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