Bleomycin
CAS No. : 11056-06-7
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| Cat. No. : | HY-108345 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Bleomycin is a glycopeptide antibiotic. Bleomycin has potent antitumour activities against a range of lymphomas, head and neck cancers and germ-cell tumours. Bleomycin can be used for the research of cancer and chemotherapy[1][2][3][4]. In Vitro:Bleomycin (0-4 mU/mL; 1 h) induces double-strand break in V79 cells[2]. Bleomycin (0-1 mU/mL; 1 h) reduces migration of DNA from S-phase cells[2]. Bleomycin (0-3 μg/mL; 1 h) induces chromatid aberrations in G2 cells[3]. In Vivo:Bleomycin (1 mg and 10 μg; retro-orbitary sinus injection once) affects cells in mitosis, induces apoptosis in tumor models[4].
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