Ridogrel


CAS No. : 110140-89-1

(Synonyms: R 68070)

110140-89-1
Price and Availability of CAS No. : 110140-89-1
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5mg $90 In-stock
10mg $139 In-stock
25mg $256 In-stock
50mg $420 In-stock
100mg $672 In-stock
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Cat. No. : HY-A0221
M.Wt: 366.33
Formula: C18H17F3N2O3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 110140-89-1 :

Ridogrel (R 68070) is an orally active combined thromboxane A2 synthetase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor blocker. Ridogrel is potent antiplatelet agent. Anti-inflammatory activities[1][2][3]. In Vitro: In rats, R 68 070 (1.25 mg/kg orally, -2 h) singly prolongs tail bleeding times as much as a combination of TXA2 synthetase inhibition (dazoxiben 10 mg/kg) and TXA2/prostaglandin endoperoxide receptor blockade (BM 13177 40 mg/kg). In dogs, the compound reduces coronary thrombosis induced by electrical damage (1.25 mg/kg i.v.) and prevents the evolution of occlusion/reperfusion-induced arrhythmias into ventricular fibrillation (2.5 mg/kg i.v.)[2.

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