ALLM


CAS No. : 110115-07-6

(Synonyms: Calpain inhibitor II)

110115-07-6
Price and Availability of CAS No. : 110115-07-6
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1mg $60 In-stock
5mg $185 In-stock
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Cat. No. : HY-118355
M.Wt: 401.56
Formula: C19H35N3O4S
Purity: >98 %
Solubility: DMSO : ≥ 20 mg/mL
Introduction of 110115-07-6 :

ALLM (Calpain inhibitor II) is a potent inhibitor of calpain and cathepsin proteases. ALLM inhibits neuronal cell death and improves chronic neurological function after spinal cord injury (SCI)[1][2]. In Vivo: ALLM (Calpain inhibitor II) (0.5 mg/kg) is injected every 24 h for 5 days after SCI and inhibits the activation of calpain but not that of caspase 3. ALLM prevents this neuronal cell death[2].
ALLM (0.05-2.5 mg/kg; i.p.; every 24 h for 1 week) reduces motor disturbances after spinal cord injury (SCI)[2].

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