MG-101


CAS No. : 110044-82-1

(Synonyms: Calpain inhibitor I; Ac-LLnL-CHO; ALLN)

110044-82-1
Price and Availability of CAS No. : 110044-82-1
Size Price Stock
5mg $60 In-stock
10mg $90 In-stock
25mg $190 In-stock
50mg $300 In-stock
100mg $480 In-stock
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Cat. No. : HY-18964
M.Wt: 383.53
Formula: C20H37N3O4
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 110044-82-1 :

MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer[1]. In Vitro: MG-101 (0-26 μM; 24 h) affects the growth of colon cancer HCT116 cells[1].
MG-101 (0-26 μM; 24 h) induces apoptosis of various cancer cells[1].
MG-101 (0-26 μM; 24 h) induces Bax-dependent apoptosis in HCT116 cells[1]. In Vivo: MG-101 (10 mg/kg; i.p. once daily for 15 days) inhibits tumor growth in nude mice[1].

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