Vasopressin
CAS No. : 11000-17-2
(Synonyms: Arginine vasopressin; Antidiuretic hormone)
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|---|---|---|
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| 10mg | $80 | In-stock |
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| 50mg | $200 | In-stock |
| 100mg | $290 | In-stock |
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| Cat. No. : | HY-B1811 |
| M.Wt: | 1084.23 |
| Formula: | C46H65N15O12S2 |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic) |
Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors[1][2][3].
In Vitro: AVP (0.01 nM-1 μM) induces Ca2+ increase in Chinese hamster ovary cells expressing rat or human V1b receptors[2].
In Vivo: Vasopressin (0.03-0.3 μg/kg; i.p.) potentiates corticotropin release provoked by exogenous corticoliberin and increases corticotropin secretion subsequent to body water loss[2].
Vasopressin (0.001-0.1 mg/kg; i.p.) potently increases adjacent lying, where rats meeting for the first time lie passively next to each other[3].
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