Kifunensine


CAS No. : 109944-15-2

(Synonyms: FR-900494)

109944-15-2
Price and Availability of CAS No. : 109944-15-2
Size Price Stock
5mg $180 In-stock
10mg $280 In-stock
25mg $590 In-stock
50mg $975 In-stock
100mg $1650 In-stock
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Cat. No. : HY-19332
M.Wt: 232.19
Formula: C8H12N2O6
Purity: >98 %
Solubility: DMSO : 11.9 mg/mL (ultrasonic)
Introduction of 109944-15-2 :

Kifunensine, a potent and selective inhibitor of class I α-mannosidases isolated from Actinomycete, prevents α-mannosidases I from trimming mannose residues on glycoproteins. Kifunensine inhibits ERAD[1][2][3]. In Vitro: Kifunensine, an alkaloid from actinomycete Kitasatosporia kifunense 9482, is the most efficient nhibitor of a-mannosidase I, blocking N-glycan synthesis at an8GlcNAc2 (Man8) or Man9GlcNAc2 (Man9) stage[3].

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