Vedroprevir
CAS No. : 1098189-15-1
(Synonyms: GS-9451)
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| Cat. No. : | HY-16773 |
| M.Wt: | 910.52 |
| Formula: | C45H60ClN7O9S |
| Purity: | >98 % |
| Solubility: |
Vedroprevir (GS-9451) is an inhibitor for HCV NS3/4A protease with an IC50 of 3.2 nM. Vedroprevir is also an inhibitor for breast cancer resistant protein (BCRP) with an IC50 of 1.4 μM. Vedroprevir inhibits P-gp, MRP1 and MRP2 with IC50 of 34, 14.9 and 12 μM, respectively. Vedroprevir exhibits good pharmacokinetic characteristics in rats and dogs[1]. IC50 & Target:IC50: 3.2 nM (HCV NS3/4A protease), 1.4 μM (BCRP), 34 μM (P-gp), 14.9 μM (MRP1), 12 μM (MRP2)
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