(2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride


CAS No. : 109628-38-8

109628-38-8
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Cat. No. : HY-113902
M.Wt: 409.95
Formula: C24H28ClN3O
Purity: >98 %
Solubility:
Introduction of 109628-38-8 :

(2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride (compound 1AA) is a SETBP1 inhibitor that disrupts the interaction between SETBP1 and XPO1. (2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride inhibits colony formation, induces differentiation/cytotoxicity, and downregulates the transcription of Setbpl target genes. (2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride improves survival and reduces the spleen size of leukemic mice. (2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride can be used for myeloid neoplasms and solid tumors research[1].

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