2-Methoxyidazoxan (monohydrochloride)
CAS No. : 109544-45-8
(Synonyms: RX821002 (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $80 | In-stock |
| 25mg | $168 | In-stock |
| 50mg | $270 | In-stock |
| 100mg | $430 | In-stock |
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| Cat. No. : | HY-103197 |
| M.Wt: | 270.71 |
| Formula: | C12H15ClN2O3 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
2-Methoxyidazoxan monohydrochloride (RX821002 hydrochloride) is a highly selective alpha 2-adrenoceptor antagonist with little or no imidazoline antagonist effect. RX 821002 has markedly higher affinity for (guinea-pig) alpha 2D-adrenoceptors (pKd 9.7) than for (rabbit) alpha 2A-adrenoceptors (pKd 8.2)[1][2]. In Vivo: 2-Methoxyidazoxan monohydrochloride (1 mg/kg) enhances locomotion in the novel environment, particularly in neonatal ventral hippocampal lesion (NVHL) rats. RX82100 has a biphasic effect on locomotion, consisting of an initial reduction preceding the enhancement[3].
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- 2-Methoxyidazoxan (monohydrochloride)
- Cat. No.:
- HY-103197
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