Epetraborole
CAS No. : 1093643-37-8
(Synonyms: GSK-2251052; AN 3365)
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| Cat. No. : | HY-12479 |
| M.Wt: | 237.06 |
| Formula: | C11H16BNO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Epetraborole (GSK2251052) is a leucyl-tRNA synthetase (LeuRS) inhibitor (IC50=0.31 μM), thereby inhibiting protein synthesis. Epetraborole can be used in multidrug-resistant gram-negative pathogens infection research[1][2][3]. IC50 & Target:IC50: 0.31 μM (LeuRS)[3] In Vitro:Epetraborole (0-32 μg/mL) shows anti-bacterial activity against key gram-negative aerobic and anaerobic pathogens and gram-positive anaerobes[1].
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