GW780056X
CAS No. : 1093294-48-4
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| Cat. No. : | HY-114567 |
| M.Wt: | 373.46 |
| Formula: | C21H23N7 |
| Purity: | >98 % |
| Solubility: |
GW780056X is a CDK12 inhibitor. GW780056X decreases nuclear foci count in DM1 cells. GW780056X can be used for the research of myotonic dystrophy type 1[1].
In Vitro:GW780056X (0.1-10 μM; 24 h) reduces nuclear foci in DM1 fibroblast cells in a dose-dependent manner[1].
GW780056X (2 μM) binds to CDK12 in K562 cell extracts, and this binding affinity correlates strongly with its nuclear foci-reducing activity in DM1 cells[1].
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