Eicosapentaenoyl ethanolamide
CAS No. : 109001-03-8
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| Cat. No. : | HY-124089 |
| M.Wt: | 345.52 |
| Formula: | C22H35NO2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Eicosapentaenoyl ethanolamide, an omega-3 fatty acid, is one of N-acylethanolamines (NAEs). Eicosapentaenoyl ethanolamide is cannabinoid CB1/CB2 receptor agonist. Eicosapentaenoyl ethanolamide acts as a metabolic signal. Eicosapentaenoyl ethanolamide inhibits dietary restriction (DR)-induced lifespan extension in wild type animals and suppresses lifespan extension in a TOR pathway mutant[1][2]. In Vitro: Eicosapentaenoyl ethanolamide (EPEA) induces cell death in both LNCaP and PC3 cells (IC50=16.19 μM). EPEA (24 hours) did not result in any significant changes in the G1, S or G2 phases of the cell cycle[1].
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