Nemorubicin (GMP)
CAS No. : 108852-90-0
(Synonyms: Methoxymorpholinyl doxorubicin (GMP); FCE 23762 (GMP); PNU 152243 (GMP))
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| Cat. No. : | HY-15794G |
| M.Wt: | 643.64 |
| Formula: | C32H37NO13 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO;10 mM in DMSO |
Nemorubicin (Methoxymorpholinyl doxorubicin) GMP is a GMP-class Nemorubicin (HY-15794). Nemorubicin is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair (NER) system to exert its activity[1][2][3][4].
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