KLK5/14-IN-1
CAS No. : 1087624-28-9
| Size | Price | Stock |
|---|---|---|
| 100mg | $486 | Get quote |
| 250mg | $692 | Get quote |
| 500mg | $1091 | Get quote |
| 1g | $1400 | Get quote |
| 5g | $4058 | Get quote |
| 10g | $6015 | Get quote |
| 50 g | Get quote | |
| 100 g | Get quote | |
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| Cat. No. : | HY-100497 |
| M.Wt: | 343.40 |
| Formula: | C18H17NO4S |
| Purity: | >98 % |
| Solubility: |
KLK5/14-IN-1 is a selective human skin kallikrein inhibitor with IC50 values of 0.048 μM, 0.2 μM, and 0.1 μM for KLK7, KLK5, and KLK14, respectively. KLK5/14-IN-1 shows no or only low inhibitory activity against Cathepsin G, Chymotrypsin, Trypsin, and Thrombin. KLK5/14-IN-1 can be used in research related to Netherton syndrome[1].
In Vitro:KLK5/14-IN-1 (compound 1) (0.1-10 μM) selectively inhibits recombinant human KLK7, KLK5, and KLK14 with IC50 values of 0.048 μM, 0.2 μM, and 0.1 μM, respectively[1].
KLK5/14-IN-1 (0.1-10 μM) does not inhibit Cathepsin G, Chymotrypsin, Trypsin, and Thrombin, with IC50 values greater than 10 μM[1].
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- KLK5/14-IN-1
- Cat. No.:
- HY-100497
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