(S)-CR8


CAS No. : 1084893-56-0

1084893-56-0
Price and Availability of CAS No. : 1084893-56-0
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1mg $128 In-stock
5mg $320 In-stock
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Cat. No. : HY-112371
M.Wt: 431.53
Formula: C24H29N7O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1084893-56-0 :

(S)-CR8 is the S-isomer of CR8. (S)-CR8 is a potent and selective CDK inhibitor with IC50s of 0.060, 0.080, 0.11, 0.12, and 0.15 μM for CDK2/cyclin E, CDK2/cyclin A, CDK9/cyclin T, CDK5/p25, and CDK1/cyclin B, respectively. (S)-CR8 reduces SH-SY5Y cells survival (IC50 0.40 μM)[1].

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