Magainin 1
CAS No. : 108433-99-4
(Synonyms: Magainin I)
| Size | Price | Stock |
|---|---|---|
| 500μg | $84 | Get quote |
| 1mg | $144 | In-stock |
| 5mg | $360 | In-stock |
| 10mg | $560 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-P0269 |
| M.Wt: | 2409.85 |
| Formula: | C112H177N29O28S |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
Magainin 1 (Magainin I) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria[1][2][3]. In Vitro: Magainin 1 interacts with acidic lipids through electrostatic interactions followed by hydrophobic interactions to form an amphiphilic helix, inducing the leakage. Magainin 1 induces the leakage of calcein specifically out of negatively-charged vesicles. The peptide binds to bovine brain phosphatidylserine sonicated vesicles according to the Langmuir isotherm with a binding constant of 3.8×105 M-1 and a binding-site number of 0.10 per lipid molecule[2].
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