RB-90740


CAS No. : 108307-65-9

108307-65-9
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Cat. No. : HY-118722
M.Wt: 362.43
Formula: C20H22N6O
Purity: >98 %
Solubility:
Introduction of 108307-65-9 :

RB-90740 is a type of biological reducing agent. RB-90740 is activated through metabolic reduction and generates cytotoxic products, thereby selectively killing tumor cells (usually in a hypoxic environment). RB-90740 has selective toxicity towards hypoxic cells, which is mainly achieved by causing DNA strand breaks and activating reducing enzymes (such as Cytochrome P450). RB-90740 does not initially exhibit cytotoxicity similar to its in vitro properties in hypoxic cells in mouse models. RB-90740 can be used to study the tumor physiological environment[1][2]

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