RCGD423
CAS No. : 108237-91-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $90 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $200 | In-stock |
| 50mg | $290 | In-stock |
| 100mg | $450 | In-stock |
| 200mg | $720 | In-stock |
| 500 mg | Get quote | |
| 1 g | Get quote | |
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| Cat. No. : | HY-114775 |
| M.Wt: | 331.23 |
| Formula: | C15H11BrN2S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair. IC50 & Target: gp130[1] In Vitro: RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair[1]. In Vivo: RCGD423 greatly reduces chondrocyte hypertrophy, loss and degeneration while increasing chondrocyte proliferation beyond that observed in response to injury in a rat partial meniscectomy model. Moreover, RCGD 423 improves cartilage healing in a rat full-thickness osteochondral defect model, increasing proliferation of mesenchymal cells in the defect and also inhibiting breakdown of cartilage matrix in de novo generated cartilage[1].
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