Benzamide Derivative 1


CAS No. : 108226-05-7

108226-05-7
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Cat. No. : HY-U00415
M.Wt: 423.98
Formula: C22H34ClN3O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 108226-05-7 :

Benzamide Derivative 1 is a benzamide derivative from patent EP0213775A1, compound 18. Benzamide Derivative 1 may be useful in treatment of gastrointestinal disorders. IC50 & Target: Dopamine, mACh receptor[1] In Vitro: Substituted benzamides have been shown to possess a number of pharmacological properties most of which are related to their ability to antagonize the central and peripheral effects of dopamine and/or facilitate the release of acetylcholine on to muscarinic receptors in the gastrointestinal smooth muscle. This has led to their successful clinical use as antiemetic and in the treatment of a wide range of gastrointestinal disorders of somatic, psychosomatic and iatrogenic origin[1].

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