LY256548
CAS No. : 107889-31-6
(Synonyms: LY25684)
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| Cat. No. : | HY-114873 |
| M.Wt: | 333.49 |
| Formula: | C19H27NO2S |
| Purity: | >98 % |
| Solubility: |
LY256548 (LY25648) is an orally available anti-ischemic and anti-inflammatory compound with central nervous system activity. LY256548 is an inhibitor of phospholipase A2, 5-lipoxygenase (5-LOX), and COX, and inhibits A23187 (HY-N6687)-stimulated leukotriene B4 production. LY256548 inhibits bone damage and paw swelling in the rat Freund's complete adjuvant-induced arthritis (FCA) model[1][2]. In Vivo: The oral absorption of LY256548 (LY25648) in rats, dogs, and monkeys was 45%, 7%, and 12%, respectively, and the systemic bioavailability was 6%, 0.4%, and 3%, respectively[1].
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