PF-04418948


CAS No. : 1078166-57-0

1078166-57-0
Price and Availability of CAS No. : 1078166-57-0
Size Price Stock
1mg $36 In-stock
5mg $77 In-stock
10mg $115 In-stock
50mg $484 In-stock
100mg $532 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-18966
M.Wt: 409.41
Formula: C23H20FNO5
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 1078166-57-0 :

PF-04418948 is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM[1]. In Vitro: PF-04418948 (2 μM; 90 min) inhibits prostaglandin E2 (PGE2)-induced increase in cAMP[1]. In Vivo: PF-04418948 (oral gavage; 1, 3, and 10 mg/kg; once) attenuats the butaprost-induced cutaneous blood flow response[1].

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