A-802715


CAS No. : 107767-58-8

107767-58-8
Price and Availability of CAS No. : 107767-58-8
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10mg $440 In-stock
25mg $880 In-stock
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100mg $2180 In-stock
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Cat. No. : HY-U00142
M.Wt: 322.40
Formula: C16H26N4O3
Purity: >98 %
Solubility: DMSO : 190 mg/mL (ultrasonic)
Introduction of 107767-58-8 :

A802715 is a methylxanthine derivative. A802715 has a TD50 (toxic dose of 50%) of 0.9-1.1 mM. In Vitro: The toxicity of the methylxanthine derivative A802715 is determined against the two human melanoma lines, Be11 and MeWo, and against the two human squamous cell carcinoma lines, 4197 and 4451, by vital dye staining assay. A802715 has a TD50 of 0.9-1.1 mM and is the most toxic. In p53 wt cells BrdU incorporations show that the irradiation-induced suppression of S-phase entry is strongly enhanced by A802715. A802715 prolongs the G2/M block or remain ineffective depending on the p53 status of the cell line[1].

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