Eplerenone
CAS No. : 107724-20-9
(Synonyms: Epoxymexrenone)
| Size | Price | Stock |
|---|---|---|
| 5mg | $56 | In-stock |
| 10mg | $88 | In-stock |
| 25mg | $175 | In-stock |
| 50mg | $259 | In-stock |
| 100mg | $354 | In-stock |
| 500mg | $810 | In-stock |
| 1g | $950 | In-stock |
| 5 g | Get quote | |
| 10 g | Get quote | |
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| Cat. No. : | HY-B0251 |
| M.Wt: | 414.49 |
| Formula: | C24H30O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV)[1][2]. IC50 & Target:IC50: 0.081 μM (human mineralocorticoid receptor) [2] In Vitro: Eplerenone inhibits the human mineralocorticoid receptor with IC50 value of 0.081 μM[2]. In Vivo: Eplerenone (oral, 200 mg/kg/day for 3 months) significantly reduces oxidative stress and atherosclerosis progression in atherosclerotic apolipoprotein edeficient (EO) mice[3].
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