WIN 54954


CAS No. : 107355-45-3

107355-45-3
Price and Availability of CAS No. : 107355-45-3
Size Price Stock
5mg $135 In-stock
10mg $216 In-stock
25mg $390 In-stock
50mg $625 In-stock
100mg $1000 In-stock
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500 mg Get quote
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Cat. No. : HY-106296
M.Wt: 383.27
Formula: C18H20Cl2N2O3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 107355-45-3 :

WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections[1][2]. In Vitro: WIN 54954 reduces plaque formation of 50 of 52 rhinovirus serotypes (MICs ranges from 0.007 to 2.2 μg/mL)[1]. WIN 54954 inhibits 15 commonly isolated enteroviruses, with an EC80 of 0.06 μg/mL[1]. In Vivo: WIN 54954 (2-100 mg/kg; p.o.) protects 50% of the mice from developing paralysis following infection with coxsackievirus A-9 and echovirus-9 at the dose of 2 and 100 mg/kg, respectively[1].

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