Kazusamycin B
CAS No. : 107140-30-7
(Synonyms: PD 124895; CL-1957E)
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| Cat. No. : | HY-118331 |
| M.Wt: | 542.70 |
| Formula: | C32H46O7 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Kazusamycin B is an antibiotic that could be isolated from the fermentation broth of Streptomyces sp. No. 81-484. Kazusamycin B inhibits cell growth and arrests cell cycle at G1 phase. Kazusamycin B can be used in research of cancer[1][2].
In Vitro:Kazusamycin B (PD 124895; 5 ng/mL; 24 h; 1210 cells) has cell cytotoxicity in a time-dependent manner and arrests cell cycle at G1 phase[2].
Kazusamycin B (5-50 ng/mL; 0-6 h; 1210 cells) B inhibits RNA synthesis moderately but specifically at 2 hours[2].
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