RU 24969 (succinate)
CAS No. : 107008-28-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $72 | In-stock |
| 10mg | $102 | In-stock |
| 50mg | $360 | In-stock |
| 100mg | $550 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-16688A |
| M.Wt: | 346.38 |
| Formula: | C18H22N2O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 120 mg/mL (ultrasonic) |
RU 24969 succinate is a 5-HT receptor agonist with Ki values of 0.38 and 2.5 nM for 5-HT1B and 5-HT1A, respectively. RU 24969 decreases fluid consumption and increases forward locomotion. RU 24969 succinate can be used for the research of neurological disease[1][2][3][4]. IC50 & Target:Ki: 0.38 nM (5-HT1B), 2.5 nM (5-HT1A)[3] In Vitro:RU 24969 succinate (30 nM-1 μM) dose-dependently inhibits K+ evoked efflux of tritium and shows a pD2 value of 7.45 for the maximum effect at 1 μM[1]. In Vivo:RU 24969 succinate (1 and 3 mg/kg; s.c., once) potentiates cocaine-induced effects[2]. RU 24969 succinate (0.03-3.0 mg/kg; s.c., once) dose-dependently decreases water consumption in water deprived rats[4].
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