Sarcosine
CAS No. : 107-97-1
(Synonyms: N-Methylglycine; Sarcosin)
| Size | Price | Stock |
|---|---|---|
| 25g | $5 | In-stock |
| 100g | $13 | In-stock |
| 500g | $42 | In-stock |
| 1000g | $84 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-101037 |
| M.Wt: | 89.09 |
| Formula: | C3H7NO2 |
| Purity: | >98 % |
| Solubility: | DMSO : < 1 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic) |
Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].
IC50 & Target:GlyT1, NMDA[1]
In Vivo: Sarcosine (400-800mg/kg; i.p.) significantly raises the threshold for electroconvulsions[2].
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