Olprinone (Standard)
CAS No. : 106730-54-5
(Synonyms: Loprinone (Standard))
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| Cat. No. : | HY-14254AR |
| M.Wt: | 250.26 |
| Formula: | C14H10N4O |
| Purity: | >98 % |
| Solubility: |
Olprinone (Standard) is the analytical standard of Olprinone (HY-14254A). This product is intended for research and analytical applications. Olprinone (Loprinone) is a potent and selective phosphodiesterase 3 (PDE3) inhibitor, with IC50 values of 150, 100, 0.35, and 14 μM against PDE1, PDE2, PDE3, and PDE4, respectively. Olprinone exerts comprehensive protective effects including anti-inflammatory, antioxidant, and anti-apoptotic activities by elevating intracellular cAMP levels and inhibiting the NF-κB and MAPK signaling pathways. Olprinone can be used in studies related to lung injury, spinal cord injury, myocardial ischemia-reperfusion injury, and cerebral ischemic injury[1][2][3][4][5][6].
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