Tafenoquine (Succinate)
CAS No. : 106635-81-8
(Synonyms: WR 238605 (Succinate))
| Size | Price | Stock |
|---|---|---|
| 5mg | $70 | In-stock |
| 10mg | $103 | In-stock |
| 25mg | $210 | In-stock |
| 50mg | $355 | In-stock |
| 100mg | $600 | In-stock |
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| Cat. No. : | HY-111529A |
| M.Wt: | 581.58 |
| Formula: | C28H34F3N3O7 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Tafenoquine Succinate (WR 238605 Succinate) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent[1]. IC50 & Target: Anti-malarial[1] In Vivo: Tafenoquine exhibits no anti-malarial activity in CYP 2D knock-out mice when dosed at their ED100 values (3 mg/kg) established in WT mice. Tafenoquine anti-malarial activity is partially restored in humanized/CYP 2D6 knock-in mice when tested at two times its ED100 (6 mg/kg)[1].
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