SMND-309


CAS No. : 1065559-56-9

1065559-56-9
Price and Availability of CAS No. : 1065559-56-9
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1mg $480 In-stock
5mg $1200 In-stock
10mg $1920 In-stock
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Cat. No. : HY-13056
M.Wt: 358.30
Formula: C18H14O8
Purity: >98 %
Solubility: DMSO : ≥ 3.7 mg/mL
Introduction of 1065559-56-9 :

SMND-309 is a metabolite of salvianolic acid B, and exhibits neuroprotective effects in cultured neurons and in permanent middle cerebral artery occlusion rats[1][2]. In Vivo: SMND-309 (2.5-10 mg/kg; oral intragastric; once a day; for 4 weeks; male Sprague-Dawley rats) treatment ameliorates liver function and decreases the elevation of serum hyaluronic acid, laminin, procollagen type III levels and hydroxyproline content in liver tissue. SMND-309 also decreases the elevation in the malondialdehyde level and restored the decrease in superoxide dismutase and glutathione peroxidase activities. SMND-309 treatment reduces the liver damage and the liver fibrosis grade. SMND-309 treatment powerfully down-regulated the expression of connective tissue growth factor (CTGF) in serum and liver[1].

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