NSC 140873
CAS No. : 106410-13-3
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| Cat. No. : | HY-118365 |
| M.Wt: | 277.71 |
| Formula: | C13H12ClN3O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
NSC 140873 is an inhibitor of the RUNX1-CBFβ interaction. NSC 140873 can be used for research of viral infection and leukemia. NSC 140873 has an unstable structure and can be converted spontaneously in solution to a benzodiazepine (Ro5-3335)[1][2].
In Vitro:NSC 140873 (1 to 100 μM, 5-6 days) reduces definitive hematopoiesis in the zebrafish embryos[2].
NSC 140873 has antiproliferative activities against cells with high RUNX1 expression[2].
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