ICI 185282
CAS No. : 106393-80-0
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| Cat. No. : | HY-101235 |
| M.Wt: | 374.35 |
| Formula: | C18H21F3O5 |
| Purity: | >98 % |
| Solubility: |
ICI 185282 is a potent, selective, orally active thromboxane A2 (TXA₂) receptor antagonist. ICI 185282 causes dose-dependent inhibition of U-46619 (HY-108566)-induced platelet aggregation ex-vivo in guinea-pig. ICI 185,282 inhibits bronchospasm induced by U-46619, PGD2 (HY-101988), PGF2α (HY-12956), arachidonic acid (HY-109590), LTD4 and PAF (HY-108635) in vivo. ICI 185282 can be used for bronchial asthma research[1].
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