Lei-Dab7
CAS No. : 1061556-49-7
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| Cat. No. : | HY-P1424 |
| M.Wt: | 3392.06 |
| Formula: | C141H236N46O39S6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Lei-Dab7 is a potent and selective SK2 (KCa2.2) channels blocker with a Kd of 3.8 nM. Lei-Dab7 shows low or no activity on KCa1, KCa3, Kv and Kir2.1 channels[1][2]. In Vivo: Intracerebroventricular (9-5 ng) injections of Lei-Dab7 decreases locomotor activity, food intake and body weight in rats deprived of food. A dose of 3 ng Lei-Dab7 has no effect on these types of behavior[3].
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