β-Interleukin I (163-171), human
CAS No. : 106021-96-9
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| Cat. No. : | HY-113893 |
| M.Wt: | 1004.99 |
| Formula: | C39H64N12O19 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
β-Interleukin I (163-171), human, an immunostimulatory fragment of human IL-1β peptide, is a T cell activator. β-Interleukin I (163-171), human is not an IL-1R-binding domain of IL-1β. β-Interleukin I (163-171), human is a potent adjuvant that enhances the immune response in a variety of exptl. situations[1][3][4].
In Vitro:β-Interleukin I (163-171), human (12.5-400 μg/mL, 72 h) stimulates mouse thymocyte proliferation[6].
In Vivo:β-Interleukin I (163-171), human (50 μg, daily, a poorly immunogenic fibrosarcoma (CE-2) of BALB/c mice model) induces a consistent but limited inhibition of tumor growth[2].
β-Interleukin I (163-171), human (1 μmole/kg, i.v.) together with the T-dependent antigen SRBC increases the primary immune response against the antigen[3].
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