KS370G


CAS No. : 105955-01-9

105955-01-9
Price and Availability of CAS No. : 105955-01-9
Size Price Stock
5mg $75 In-stock
10mg $125 In-stock
25mg $250 In-stock
50mg $400 In-stock
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200 mg Get quote
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Cat. No. : HY-114683
M.Wt: 283.32
Formula: C17H17NO3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 105955-01-9 :

KS370G is an orally active hypoglycemic and cardiovascular protective agent. KS370G improves left ventricular hypertrophy and function in pressure-overload mice heart. KS370G reduces renal obstructive nephropathy[1][2]. In Vivo:KS370G (1 mg/kg; oral; once daily for 8 weeks) improves left ventricular function and inhibited cardiac hypertrophy through the decrease of the phosphorylation of ERK, AKT and GSK3β in pressure-overload mice heart[1].
KS370G (10 mg/kg; oral; once daily for 13 days) attenuates unilateral ureteral obstruction-induced renal fibrosis by the reduction of inflammation and oxidative stress in mice[2].

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