H-Tyr-Tyr-OH


CAS No. : 1050-28-8

(Synonyms: L-Tyrosyl-L-tyrosine)

1050-28-8
Price and Availability of CAS No. : 1050-28-8
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100mg $111 In-stock
250mg $190 In-stock
1g $380 In-stock
5g $1899 In-stock
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Cat. No. : HY-114782
M.Wt: 344.37
Formula: C18H20N2O5
Purity: >98 %
Solubility: H2O : 100 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic)
Introduction of 1050-28-8 :

H-Tyr-Tyr-OH (L-Tyrosyl-L-tyrosine) is an antihypertensive peptide. H-Tyr-Tyr-OH inhibits angiotensin I-converting enzyme (ACE) with an IC50 value of 0.028 mg/mL. H-Tyr-Tyr-OH can be used for the research of high blood pressure[1][2]. IC50 & Target:IC50: 0.028 mg/mL (ACE)[2] In Vitro: H-Tyr-Tyr-OH shows inhibitory effect against ACE with an IC50 value of 0.028 mg/mL[2]. In Vivo: H-Tyr-Tyr-OH (12.5 mg/kg; intraarterial injection once) effects systolic blood pressure in vivo[1].
H-Tyr-Tyr-OH (0-100 mg/kg; i.p. once) effects blood pressure of spontaneously hypertensive rats[1].

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