Methyl acetylacetate


CAS No. : 105-45-3

(Synonyms: Acetoacetate methyl ester; Methyl 3-oxobutanoate; Methyl acetoacetate)

105-45-3
Price and Availability of CAS No. : 105-45-3
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Cat. No. : HY-Y1298
M.Wt: 116.12
Formula: C5H8O3
Purity: >98 %
Solubility: H2O : 100 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic)
Introduction of 105-45-3 :

Methyl acetylacetate is a chemical reagent used in the synthesis of pharmaceuticals for the synthesis of α-substituted acetoacetate and cyclic compounds such as pyrazole, pyrimidine, and coumarin derivatives. Methyl acetoacetate can be used in the study of inflammatory diseases[1][2][3]. In Vitro:Methyl acetoacetate does not induce binucleated cells with micronuclei when tested up to cytotoxic levels or the maximum concentration recommended in either non-activated or S9-activated test systems[2].
In Vivo:Methyl acetoacetate (100-1000 mg/kg/day, gavage, daily for 4 weeks) shows no treatment-related adverse effects in rats[2].

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