PS-1145 (dihydrochloride)


CAS No. : 1049743-58-9

1049743-58-9
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Cat. No. : HY-107593
M.Wt: 395.67
Formula: C17H13Cl3N4O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1049743-58-9 :

PS-1145 (dihydrochloride) is a potent IκB kinase-2 inhibitor with an IC50 value of 88 nM. PS-1145 (dihydrochloride) inhibits activity of NF-κB by blocking IκB kinase phosphorylation in tumor-bearing rats[1]. IC50 & Target: IC50: 88 nM (IκB kinase-2)[1]

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