MK-5596


CAS No. : 1044586-68-6

1044586-68-6
Price and Availability of CAS No. : 1044586-68-6
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Cat. No. : HY-10575
M.Wt: 541.86
Formula: C27H23Cl3N4O2
Purity: >98 %
Solubility:
Introduction of 1044586-68-6 :

MK-5596 is an efficient, selective and orally active CB1R (IC50 = 1.0 nM, EC50 = 5.8 nM) inverse agonist. MK-5596 has weak hERG inhibitory activity. MK-5596 has strong weight loss and appetite suppression effects. MK-5596 has a certain inhibitory effect on CYP enzymes (CYP3A4: IC50 = 3.3 μM, CYP2C8: IC50 = 11 μM, CYP2C9: IC50 = 18 μM, CYP2D6: IC50 = 6 μM). MK-5596 can be used for research on conditions such as obesity[1].

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