Angiotensinogen (1-14), human
CAS No. : 104180-23-6
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| Cat. No. : | HY-P1486 |
| M.Wt: | 1760.01 |
| Formula: | C83H122N24O19 |
| Purity: | >98 % |
| Solubility: | H2O |
Angiotensinogen (1-14), human is a fragment of the renin substrate angiotensinogen. Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptides[1][2].
In Vitro: Angiotensinogen (AGT) is the only precursor of all angiotensin peptides. Human AGT has 485 amino acids, including a 33 amino-acid signal peptide. The 10 N-terminal amino acids are cleaved by renin to provide angiotensin I (AngI), which is the source for an array of active angiotensin peptides[1].
Angiotensinogen isolated from most species is cleaved by human renin. Synthetic peptides containing the N-terminal amino-acid sequence of angiotensinogen were renin substrates[2].
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