GCLE
CAS No. : 104146-10-3
(Synonyms: Cephalosporin G 3-chloromethyl p-methoxybenzyl ester)
| Size | Price | Stock |
|---|---|---|
| 1g | $25 | In-stock |
| 5g | $60 | In-stock |
| 10g | $100 | In-stock |
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| Cat. No. : | HY-W018563 |
| M.Wt: | 486.97 |
| Formula: | C24H23ClN2O5S |
| Purity: | >98 % |
| Solubility: |
GCLE (Cephalosporin G 3-chloromethyl p-methoxybenzyl ester) is a SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 0.03 μM. GCLE selectively acylates the Cys145 residue of Mpro. GCLE is applicable to research related to COVID-19[1]. In Vitro:GCLE (5-20 μM) modestly reduces SARS-CoV-2 replication in infected VeroE6 cells at 20 μM, though it shows no activity at 5 μM and exhibits cytotoxicity at active concentrations[1].
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