1-(1-Naphthyl)piperazine (hydrochloride)
CAS No. : 104113-71-5
(Synonyms: 1-NP (hydrochloride); 1-Naphthylpiperazine (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 100mg | $310 | Get quote |
| 250mg | $473 | Get quote |
| 500 mg | Get quote | |
| 1 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-112538 |
| M.Wt: | 248.75 |
| Formula: | C14H17ClN2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
1-1-Naphthylpiperazine hydrochloride (1-NP hydrochloride; 1-Naphthylpiperazine hydrochloride) is a serotonergic derivative of quipazine, which is both an agonist for 5-HT1A receptor and an antagonist for 5-HT2A receptor. 1-1-Naphthylpiperazine hydrochloride induces cell apoptosis. 1-1-Naphthylpiperazine hydrochloride prevents the immunosuppression and photocarcinogenesis[1].
In Vitro:1-1-Naphthylpiperazine hydrochloride (50-300 μM) suppresses the melanoma cells MNT-1 with an IC50 is 163.6 μM, by inducing the cell cycle arrest at S-phase, cell apoptosis and ROS generation[1].
1-1-Naphthylpiperazine hydrochloride (0-200 μM) regulates the expressions of related genes, which are associated with the UV-induced immunosuppression[1].
In Vivo:1-1-Naphthylpiperazine hydrochloride (1 μM, i.p., single dose) promotes the DNA repair induced by UV radiation through the mechanism involving nucleotid excision repair(NER), which prevents the immune suppression and interferes the photocarcinogenesis in UVB exposed C57BL/6 mice[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- 1-(1-Naphthyl)piperazine (hydrochloride)
- Cat. No.:
- HY-112538
- Quantity:
Your information is safe with us.