S-8666
CAS No. : 103968-87-2
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| Cat. No. : | HY-113724 |
| M.Wt: | 340.18 |
| Formula: | C11H11Cl2NO5S |
| Purity: | >98 % |
| Solubility: |
S-8666 is an orally active uricosuric antihypertensive diuretic. The S-8666 has both S-(-)- and R-(+)-isomers. The diuretic and sodium-excretion activities of it are entirely dominated by the S-(-)-isomer, while the R-(+)-isomer shows no significant activity. S-8666 relies on the organic acid transport system to be secreted through the proximal tubule. S-8666 exhibits a clear uric acid excretion-promoting activity and diuretic effect in various species (such as rats and chimpanzees)[1][2].
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