Sulfadimethoxine (sodium)
CAS No. : 1037-50-9
(Synonyms: Sulphadimethoxine (sodium))
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| 500mg | $90 | In-stock |
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| Cat. No. : | HY-B0337A |
| M.Wt: | 332.31 |
| Formula: | C12H13N4NaO4S |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Sulfadimethoxine sodium (Sulphadimethoxine sodium) is a sulfonamide antibiotic. Sulfadimethoxine sodium causes a displacement of Thiopental in plasma protein binding in rats. Sulfadimethoxine sodium is used in a variety of infection studies including urinary tract infections[1][2][3][4].
IC50 & Target:Antibacterial[1]
In Vitro:Sulfadimethoxine (2.4 mM) sodium increases the apparent dissociation constant of Thiopental to serum protein by equilibrium dialysis[3].
In Vivo:Sulfadimethoxine (loading dose 200 mg/kg, then 41.3 mg/kg/h; infused through the femoral vein cannula for 3 h) sodium causes a displacement of Thiopental in plasma protein binding in rats, significantly increasing the free fraction of thiopental[3].
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