Ondansetron (hydrochloride dihydrate)
CAS No. : 103639-04-9
(Synonyms: GR 38032 (hydrochloride dihydrate); SN 307 (hydrochloride dihydrate))
| Size | Price | Stock |
|---|---|---|
| 50mg | $66 | In-stock |
| 100mg | $92 | In-stock |
| 1g | $106 | In-stock |
| 5g | $251 | In-stock |
| 10 g | Get quote | |
| 50 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-B0002A |
| M.Wt: | 365.85 |
| Formula: | C18H24ClN3O3 |
| Purity: | >98 % |
| Solubility: | H2O : 16.67 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic) |
Ondansetron (GR 38032; SN 307) hydrochloride dehydrate is a highly selective 5-HT3 receptor antagonist with an IC50 value of 103 pM. Ondansetron hydrochloride dehydrate exerts its antiemetic effect by antagonizing 5-HT receptors located in localized neurons in the peripheral and central nervous systems. Ondansetron hydrochloride dehydrate can inhibit nausea and vomiting induced by chemotherapy and radiotherapy[1][2][3][4][5][6][7][8].
In Vitro:Ondansetron (1-1000 μM) hydrochloride dehydrate dose-dependently reduces the response of EAAT3 to 30 μM L-glutamate with an IC50 of 8.57 μM[9].
In Vivo:Ondansetron (2.4-6 mg/kg; i.p.; six times over 15 days) hydrochloride dehydrate has a TD50 value of 3.7 mg/kg and an LD50 of 4.6 mg/kg[4] in mice.
Ondansetron (2 mg/kg; i.p.; six consecutive days) hydrochloride dehydrate exhibits anti-inflammatory effects in rats through the 5-HT3 receptor[8].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Ondansetron (hydrochloride dihydrate)
- Cat. No.:
- HY-B0002A
- Quantity:
Your information is safe with us.