Sumatriptan


CAS No. : 103628-46-2

(Synonyms: GR 43175 free base)

103628-46-2
Price and Availability of CAS No. : 103628-46-2
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25mg $80 In-stock
50mg $130 In-stock
100mg $210 In-stock
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Cat. No. : HY-B0121B
M.Wt: 295.41
Formula: C14H21N3O2S
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 103628-46-2 :

Sumatriptan (GR 43175) is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT1D, 5-HT1B and 5-HT1F receptors, respectively. Sumatriptan can be used for migraine headache research[1][2][3][4]. In Vivo: Sumatriptan (600 μg/kg, i.p. or 0.06 μg in 5 μL, i.t.) reverses nitroglycerin-induced thermal hypersensitivity in mice[4].

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